Please follow https://help.ubuntu.com/community/PostfixAmavisNew to install some package and startup spamassassin.
1.Edit /etc/amavis/conf.d/15-content_filter_mode
use strict;

# You can modify this file to re-enable SPAM checking through spamassassin
# and to re-enable antivirus checking.

#
# Default antivirus checking mode
# Uncomment the two lines below to enable it
#

@bypass_virus_checks_maps = (
\%bypass_virus_checks, \@bypass_virus_checks_acl, \$bypass_virus_checks_re);

#
# Default SPAM checking mode
# Uncomment the two lines below to enable it
#

@bypass_spam_checks_maps = (
\%bypass_spam_checks, \@bypass_spam_checks_acl, \$bypass_spam_checks_re);

1; # insure a defined return

2.Edit /etc/postfix/main.cf and add it:
content_filter = amavis:[127.0.0.1]:10024
receive_override_options = no_address_mappings

3.Edit /etc/postfix/master.cf and add to the end:
amavis unix - - - - 2 smtp
-o smtp_data_done_timeout=1200
-o smtp_send_xforward_command=yes
127.0.0.1:10025 inet n - - - - smtpd
-o content_filter=
-o local_recipient_maps=
-o relay_recipient_maps=
-o smtpd_restriction_classes=
-o smtpd_client_restrictions=
-o smtpd_helo_restrictions=
-o smtpd_sender_restrictions=
-o smtpd_recipient_restrictions=permit_mynetworks,reject
-o mynetworks=127.0.0.0/8
-o strict_rfc821_envelopes=yes
-o receive_override_options=no_unknown_recipient_checks,no_header_body_checks

4.Restart amavis and postfix,it's should be work.